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Liquid Chromatograph Product List

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Easily solve difficult problems in method development! Method Development LC System

Easily solve difficult problems in method development! Method Development LC System

A liquid chromatography (LC) system capable of automatic screening in a single process.

The flexibility and performance of the "1290 Infinity II Method Development System" allow for the easy and highly efficient resolution of complex method development issues. It is possible to automatically screen over 1300 different LC separation conditions in a single process. It can accommodate pressures up to 130 MPa with combinations of up to 26 solvents and 8 columns. 【Features】 ■ Utilize the excellent efficiency of UHPLC for method development ■ Automatic switching ■ Evaluate up to 1300 separation conditions ■ Develop methods for conventional LC systems from various manufacturers ■ Track used columns *For more details, please refer to the related link page or feel free to contact us.

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  • Liquid Chromatograph

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LC with flexibility that does not require removal or reconnection of columns.

LC with flexibility that does not require removal or reconnection of columns.

The daily efficiency of liquid chromatography (LC) analysis brought by reliability! Abundant modules for HPLC analysis and UHPLC analysis.

The "1260 Infinity II LC System" is equipped with a wide range of modules for HPLC and UHPLC analysis. The combination of reliable instruments, new column technologies, and advanced consumables ensures robust separation and detection performance. From sample injection to data analysis, it guarantees a reduction in total analysis time and optimization of instrument usage. Seamless method transfer and a phased upgrade path facilitate risk-free integration into existing infrastructure and enable smooth transitions within budget. 【Features】 ■ Compatible with conventional and UHPLC ■ Analysis and semi-preparative purification ■ High-speed and high-precision gradient ■ Ultra-low carryover ■ Reduced cycle time *For more details, please refer to the PDF document or feel free to contact us.

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It has a pressure resistance of up to 80 MPa, suitable for daily method development LC.

It has a pressure resistance of up to 80 MPa, suitable for daily method development LC.

Solving daily challenges in method development! A liquid chromatography (LC) system that allows for gradual upgrades of existing systems.

The "1260 Infinity II Method Development System" has a pressure resistance of up to 80 MPa and is suitable for daily method development. It allows for automatic screening under more than 100 different LC separation conditions, eliminating the need for manual operation. Method development can be conducted using up to four columns with 15 different mobile phases and two independent temperature zones. With the functionality of the new 1260 Infinity II Flexible Pump, Agilent's Intelligent System Emulation Technology (ISET) enables the emulation of selected other LC systems, allowing for the direct and seamless transfer of optimized methods to various target instruments, including those from other manufacturers. 【Features】 ■ Balanced method performance, supporting up to 80 MPa ■ ISET-equipped 1260 Infinity II Prime LC ■ Automatic screening of over 100 chromatography conditions ■ All software is Agilent products *For more details, please refer to the related links or feel free to contact us.

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Agilent 1260 Infinity II LC

Agilent 1260 Infinity II LC

Achieve a smooth transfer within budget! We guarantee robust separation and detection performance.

The "1260 Infinity II LC" is equipped with a wide range of modules for HPLC and UHPLC analysis. With easy column handling and excellent sample logistics, it ensures a reduction in total analysis time and optimization of instrument usage from sample injection to data analysis. Seamless method transfer and a stepwise upgrade path facilitate risk-free integration into existing infrastructure. **Features** - Achieves maximum operational efficiency with an efficient LC system - A combination of high-performance consumables ensures reliable separation and detection performance - Reduces analysis time and maximizes instrument utilization - Seamless method conversion and a stepwise upgrade path support smooth integration with existing infrastructure *For more details, please refer to the PDF document or feel free to contact us.*

  • Analytical Equipment and Devices
  • Liquid Chromatograph

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e-HPLC Kotori [Device demonstration available]

e-HPLC Kotori [Device demonstration available]

A liquid analysis device worth around 1 million yen that fits three on A4 paper. It can also perform field analysis. We will demonstrate the device, so please be sure to give it a try.

We have achieved miniaturization to the extent that three units can fit on A4 paper. It is a basic form of HPLC, priced around 1 million yen. This portable HPLC allows for quick and easy analysis to begin. The reasons for this are that the column is short (utilizing what is traditionally sold as a guard column) and the stabilization of the detector is rapid (using LED light sources for UV-NIR and UV-VIS). Therefore, there are benefits such as reduced reagent usage for conventional elution solvents (like carriers), decreased costs due to shorter columns, and less time spent on HPLC, allowing for more focus on other research. We have heard that it is being utilized in the research departments of companies for screening and in quality control settings. Additionally, universities are beginning to increase their use of HPLC for educational and research purposes. Even middle and high schools are using it for educational and research applications. Please consult us regarding the items or content you wish to analyze.

  • Analytical Equipment and Devices
  • Liquid Chromatograph

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Bioinert HPLC/UHPLC Arc Premier

Bioinert HPLC/UHPLC Arc Premier

Solving non-specific sample adsorption! Improved peak shape and sensitivity with new technology, featuring excellent reproducibility and durability in low-adsorption LC.

The Arc Premier system incorporates innovative technology known as MaxPeak High Performance Surfaces (HPS). This allows for the effective reduction of nonspecific adsorption due to interactions with metals, without the need for complex mobile phases or labor-intensive analytical methods. As a result, the peaks of compounds that are susceptible to metal influence become sharper, yielding the following benefits: ■ Ideal for the analysis of organic acids, organophosphates, oligonucleotides, peptides, glycoproteins, phospholipids, veterinary medicines, chelating agents, and more. ■ Improved sensitivity and reduced risk of peak omission. ■ Elimination of column and system passivation and conditioning, saving time and costs. ■ Enhanced reproducibility and reliability of results. We also offer a variety of low-adsorption columns featuring MaxPeak High Performance Surfaces (HPS) technology. When used in combination with the system, more reliable analyses can be achieved. *We also offer online briefings and demonstrations, so please feel free to contact us.

  • Analytical Equipment and Devices
  • Liquid Chromatograph

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[HPLC Case Study] Analysis of Dairy Beverages by Automatic Derivatization of Amino Acids

[HPLC Case Study] Analysis of Dairy Beverages by Automatic Derivatization of Amino Acids

High-precision and convenient automatic quantitative analysis of amino acids using the custom injection program function of an autosampler.

Many amino acids do not absorb ultraviolet (UV) light, making it difficult to improve sensitivity and selectivity with conventional analytical methods, which are also complicated and lack stability. This technical document introduces a case where a custom injection program feature in the auto-sampler of the Thermo Scientific Vanquish Core HPLC system was utilized to derivatize 20 types of amino acids simultaneously using a pre-column derivatization method for simultaneous analysis. This system enables highly accurate quantitative analysis as it is not affected by the degradation after the derivatization reaction. Validation using commercially available beverages showed that selective quantification was possible even in complex sample matrices such as food. 【Features】 ■ Simultaneous derivatization and analysis of 20 types of amino acids ■ High-precision quantitative analysis achieved through pre-column derivatization ■ Provides good linearity and high reproducibility ■ Selective detection even in complex sample matrices ■ Automation by the auto-sampler avoids human error and improves work efficiency

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  • Analytical Equipment and Devices
  • Liquid Chromatograph

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[Case Study] Analysis of Additives in Nickel Sulfate Plating Solution by HPLC

[Case Study] Analysis of Additives in Nickel Sulfate Plating Solution by HPLC

HPLC method achieving high-sensitivity quantitative analysis without complex preprocessing: Introducing quantitative know-how for quality control.

In the quality control of plating solutions, the quantification of additives is an important factor. In particular, the quantification of sulfur-containing compounds that contribute to film quality adjustment and prevention of liquid decomposition is essential. This document provides accurate and highly reproducible analytical results using a method that does not require complex pretreatment. For the HPLC measurement conditions, an ion-pair reagent was added to the mobile phase, and an injection method was adopted to reduce the influence of sample impurities. As a result, sharp peaks can be obtained without being affected by metals and inorganic ions. Additionally, by comparing the chromatograms of the standard solution and the plating solution sample, it can be confirmed that the concentration of additives is maintained consistently. Furthermore, as an evaluation of reproducibility, the same sample was measured five times, demonstrating high reproducibility. 【Features】 ■ High-sensitivity quantitative analysis without complex pretreatment ■ High reproducibility using ion-pair reagents ■ Injection method that reduces the influence of metals and inorganic ions ■ Accurate quantification through comparison of standard solutions and actual samples ■ Highly reproducible analytical results

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  • Analytical Equipment and Devices
  • Liquid Chromatograph

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Low Adsorption UPLC System ACQUITY Premier

Low Adsorption UPLC System ACQUITY Premier

Solving non-specific sample adsorption! Improved peak shape and sensitivity with new technology, featuring low adsorption and bio-inert LC with excellent reproducibility and durability.

The ACQUITY Premier system incorporates the new MaxPeak High Performance Surfaces (HPS) technology, which effectively reduces sample loss due to nonspecific adsorption caused by interactions with metals, while providing the following benefits: ■ Ideal for the analysis of organic acids, organophosphates, oligonucleotides, peptides, glycoproteins, phospholipids, veterinary drugs, chelating agents, and more. ■ Improved sensitivity and reduced risk of peak omission. ■ Elimination of column and system passivation and conditioning, saving time and costs. ■ Enhanced reproducibility and reliability of results. A variety of low-adsorption columns featuring MaxPeak High Performance Surfaces (HPS) technology are also available. When used in combination with the system, they enable more reliable analyses. *We also offer online briefings and demonstrations, so please feel free to contact us.

  • Analytical Equipment and Devices
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[Case Study] Purification of Vitamin K Isomers by Temperature-Controlled Fractionation

[Case Study] Purification of Vitamin K Isomers by Temperature-Controlled Fractionation

Demonstration of high recovery rate and isomerization suppression using normal phase HPLC with a fraction collector.

This application note presents a case study of the high-precision separation and collection of cis/trans isomers of vitamin K1 using the Thermo Scientific Vanquish Core HPLC system and Vanquish Fraction Collector. The normal phase kit extends compatibility with organic solvents such as hexane, confirming excellent reproducibility that meets EP standards (RSD < 1%). Recovery rates of 99.5% to 101.4% were achieved for both peak-based and time-based collections. Furthermore, collection and storage were conducted under temperature control, comparing isomerization behavior at 8 °C and 35 °C, demonstrating that temperature management is crucial for suppressing structural changes. For more details on reliable isomer purification using the normal phase compatible collection system, please refer to the materials. 【Features】 ■ Extended solvent compatibility with normal phase HPLC compatible kit ■ High reproducibility with retention time and peak area RSD < 1% ■ High-precision collection with recovery rates of 99.5% to 101.4% ■ Significant suppression of isomerization with low-temperature storage at 8 °C ■ Quantitative evaluation of isomerization reactions and verification of temperature dependence

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  • Analytical Equipment and Devices
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Ultra High Performance Liquid Chromatography (UV Detector) (UHPLC)

Ultra High Performance Liquid Chromatography (UV Detector) (UHPLC)

<Used Analytical Equipment>

This is the Shimadzu Nexera series ultra-fast liquid chromatography system. It features a pressure resistance of 130 MPa and a low system volume, enabling ultra-fast and high-resolution analysis. Two delivery pumps allow for high-pressure gradient measurements with two liquids. (S2758-00)

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Liquid Chromatography Comprehensive Catalog 2022-2023 Edition

Liquid Chromatography Comprehensive Catalog 2022-2023 Edition

High reliability! Liquid chromatograph that adapts to changes in application needs.

Since Agilent launched the HP1010 LC (liquid chromatography) system in 1973, it has consistently incorporated customer feedback and focused on improving system performance. During this time, there was a period when we had development and manufacturing bases in Germany and Japan (Yokogawa Electric, Yokogawa Analytical Systems), but now all LC systems are "Made in Germany." By integrating new technologies, we respond to various needs such as pharmaceutical development, food safety assurance, chemical and material analysis, and compliance with global regulations, serving users around the world. Currently, Agilent has formed a teamwork of LC instruments, columns, consumables, mass spectrometers, software, and service support under the InfinityLab series, continuously evolving to maximize daily analysis, equipment, and lab efficiency.

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Agilent 1290 Infinity II LC

Agilent 1290 Infinity II LC

Achieving throughput with various applications! A system that embodies UHPLC.

The "Agilent 1290 Infinity II LC" is a system equipped with technology that maximizes efficiency, in addition to excellent reliability and robustness. It provides outstanding separation and detection performance, significantly enhancing the reliability of analytical results. Achieving productivity and total cost of ownership through seamless integration into current lab infrastructure and smooth method transfer from traditional equipment. 【Features】 ■ Embodiment of UHPLC ■ Excellent reliability and robustness ■ Technology that maximizes efficiency ■ Achieves throughput across various applications ■ Smooth method transfer from traditional equipment *For more details, please refer to the PDF document or feel free to contact us.

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Analysis of protein aggregates by size exclusion chromatography (SEC)

Analysis of protein aggregates by size exclusion chromatography (SEC)

Evaluation by SEC is effective for protein quality control!

Quality control of proteins, including biopharmaceuticals, is important, particularly regarding aggregates such as dimers and oligomers, as well as degradation products (low molecular weight species), which have gained attention in recent years due to their relationship with immunogenicity. Size exclusion chromatography (SEC) is widely used as a simple method for analyzing these. Here, we present examples of analyses conducted on commercially available protein mixtures, IgG antibodies, and IgG antibodies that were aggregated through pH stress testing. *For more details, please refer to the PDF document or feel free to contact us.

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  • Liquid Chromatograph

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Routine HPLC systems for analysis labs and QA/QC labs.

Routine HPLC systems for analysis labs and QA/QC labs.

Achieve routine analysis LC at minimal ownership cost! Enables the use of columns with smaller particle sizes.

The "1220 Infinity II LC System" is an integrated system for routine HPLC designed for analytical and QA/QC laboratories. Based on the proven technology of the InfinityLab LC series, it delivers high quality and performance, achieving return on investment and ownership costs from the very first day of use. You can choose from four affordable "all-in-one" configurations, and when changes are needed, you can enhance system capabilities through upgrade paths. 【Features】 ■ Optimizes daily productivity ■ Complies with all LC requirements in regulated environments ■ High quality and long lifespan ■ Trouble-free and rapid startup ■ High flexibility *For more details, please refer to the PDF document or feel free to contact us.

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LC that can accurately mix buffer solutions/additives without manual operation.

LC that can accurately mix buffer solutions/additives without manual operation.

The efficiency, reliability, and convenience of liquid chromatography (LC) analysis have significantly improved! Seamlessly transfer methods across any manufacturer's LC.

The "1260 Infinity II Prime LC System" is a highly functional and convenient HPLC and UHPLC analysis system within the 1260 Infinity II LC family. It supports a maximum flow rate of 5 mL/min and a maximum pressure of 80 MPa. The precision and accuracy in separation are extremely high, significantly improving the reliability of analytical results. Automation features reduce manual tasks, providing a higher level of comfort in daily analytical operations. 【Features】 - Seamless method transfer from any manufacturer's LC - Realization of a simple workflow - Reduction of manual tasks - Ultra-low carryover - Efficient sample handling and excellent sample capacity *For more details, please refer to the PDF document or feel free to contact us.

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GPC/SEC LC designed to address the challenges of polymer analysts.

GPC/SEC LC designed to address the challenges of polymer analysts.

Accurate routine polymer analysis! Liquid chromatography (LC) allows for obtaining more information about the size and composition of polymers.

The "1260 Infinity II GPC/SEC System" is designed to address the challenges faced by polymer analysts. Equipped with a newly developed vial sampler, it improves sample throughput. The multi-column thermostat accurately controls temperature, minimizing detector noise and baseline drift. The enhanced isocratic pump achieves exceptional flow rate precision, enabling high-accuracy analysis with the new differential refractive index detector. 【Features】 ■ Accuracy: High reproducibility and consistency in molecular weight distribution ■ High performance: Significantly improved sample throughput due to rapid system stabilization ■ Versatility: Ability to perform both GPC/SEC and LC in the same system ■ Reduced solvent costs: Recyclable solvents that do not elute polymer peaks ■ Automation: Fully automated workflow with the vial sampler *For more details, please refer to the related links or feel free to contact us.

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Liquid Chromatograph 'Vanquish Neo UHPLC'

Liquid Chromatograph 'Vanquish Neo UHPLC'

All-in-one nano, capillary, and microflow LC! Achieve high-sensitivity LC-MS analysis with outstanding ease of use. *Technical materials available!

The "Vanquish Neo UHPLC System" is an all-in-one low-flow UHPLC system that delivers excellent performance at nano, capillary, and microflow rates without any hardware modifications. With a high-pressure design of 1,500 bar and an ultra-low gradient delay volume (GDV), it establishes a new standard for low-flow LC, maximizing the number of identifications in proteomics and enabling high-throughput, high-sensitivity analysis. Through an intuitively operable user interface, remote control, system status monitoring, self-checks, and guided maintenance tutorials, high-quality results can be obtained even by those who are not experts in analysis. 【Features】 ■ Supports flow rates from nano to 100 μL/min without hardware modifications ■ Vial bottom detection function allows for injection of small sample volumes ■ Improved quantitation performance due to excellent injection volume linearity and precision ■ High sample throughput achieved with high-pressure design and ultra-low GDV ■ Enhanced usability with a visually operable user interface *For more details, please refer to the PDF materials or feel free to contact us.

  • Analytical Equipment and Devices
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Functional ingredient analysis solutions for food.

Functional ingredient analysis solutions for food.

Providing solutions for routine analysis of functional ingredients and quantification of flavor components.

In recent years, "functional ingredients" that add value to food have gained attention, and various foods containing these functional ingredients are being developed, manufactured, and sold as Foods for Specified Health Uses (Tokuho) and Foods with Functional Claims. However, in the analysis of functional ingredients contained in food, achieving excellent separation and high sensitivity detection using liquid chromatography (LC) often poses challenges, making it difficult to objectively evaluate flavor components that affect taste. Waters, as a specialized manufacturer of LC and mass spectrometers, supports reliable analysis of functional claim foods with high-sensitivity mass spectrometers, as well as total solutions including LC systems, columns, and informatics that achieve high separation. ★ Application notes and on-demand webinars are now available We are currently offering application notes and various materials related to reliable routine analysis of functional ingredients and flavor components. Please check them out under "Download."

  • ACQUITY QDa検出器.jpg
  • AccQTag Ultra Derivatization Kit.jpg
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  • Analytical Equipment and Devices
  • Mass Spectrometer
  • Liquid Chromatograph

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[HPLC Case Study] Analysis of Organic Acids in Beverages Using Post-Column Analysis Method

[HPLC Case Study] Analysis of Organic Acids in Beverages Using Post-Column Analysis Method

Accurate quantification of organic acids in beverages! Introduction to the performance and convenient features of a post-column HPLC system suitable for routine analysis.

This technical document introduces a post-column analysis system for accurately quantifying organic acids in various beverages. The analysis column uses ion exclusion mode, and by adding BTB solution post-column, it separates and detects ten types of organic acids with good reproducibility. The e-workflow feature, which supports operations in routine analysis, is a significant advantage as it fully automates the process from device startup to measurement and report generation. The HPLC system features a compact design that incorporates a dual pump with two pumps in one module for analysis and post-column solution delivery. Additionally, even in the event of an error, the automatic switching of valves prevents the post-column reaction solution from backflowing into the analysis column, allowing for safe adoption in routine analysis. 【Features】 ■ Accurate quantification of ten types of organic acids with good reproducibility of less than 1% ■ Separation of organic acids using ion exclusion mode columns, allowing measurement without matrix effects ■ Detection limits for organic acids in this method range from a few to 7 μg/mL ■ Automation of the process from device startup to report generation with the e-workflow feature ■ Ensured safety with automatic valve switching in case of errors

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  • Analytical Equipment and Devices
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